The hidden hedgehog of the pituitary: hedgehog signaling in development, adulthood and disease of the hypothalamic-pituitary axis
Hedgehog signaling plays pivotal roles in embryonic development, adult homeostasis and tumorigenesis.However, its 9002nc engagement in the pituitary gland has been long underestimated although Hedgehog signaling and pituitary embryogenic development are closely linked.Thus, deregulation of this signaling pathway during pituitary development results